Two sample MR report
ELP5_Conventional Dendritic Cell against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.0058794 | 0.1673109 | 0.9731074 |
| Weighted median | 8 | -0.0251651 | 0.0077343 | 0.0011390 |
| Inverse variance weighted | 8 | -0.0256153 | 0.0063748 | 0.0000586 |
| Simple mode | 8 | -0.0249150 | 0.0112211 | 0.0618424 |
| Weighted mode | 8 | -0.0248484 | 0.0098518 | 0.0396818 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1752488 | 6 | 0.9998950 |
| Inverse variance weighted | 0.2107349 | 7 | 0.9999699 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0213499 | 0.1133356 | 0.8567906 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001255 | 0 | TRUE | 0.2898489 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
